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2 edition of Prostaglandins and cyclic AMP found in the catalog.

Prostaglandins and cyclic AMP

Symposium on the Medical Aspects of Prostaglandins and Cyclic AMP, University of Michigan 1972

Prostaglandins and cyclic AMP

biological actions and clinical applications. Edited by Raymond H. Kahn [and] William E.M. Lands.

by Symposium on the Medical Aspects of Prostaglandins and Cyclic AMP, University of Michigan 1972

  • 139 Want to read
  • 36 Currently reading

Published by Academic Press in New York .
Written in English

    Subjects:
  • Cyclic adenylic acid -- Congresses,
  • Prostaglandin -- Congresses

  • Edition Notes

    ContributionsKahn, Raymond H., Lands, William E. M., 1905-
    Classifications
    LC ClassificationsRM666 P857 S96
    The Physical Object
    Pagination306p.
    Number of Pages306
    ID Numbers
    Open LibraryOL21878478M

    Prostaglandin E1 reduces gastric secretion preventing the formation of ulcers. Prostaglandin E1 is also a potent inhibitor of platelet aggregation. Prostaglandin E1 stimulates accumulation of cyclic AMP and can stimulate thyroid activity in a manner similar to that of TSH.   Exogenous prostaglandins, like TSH, bind to thyroid plasma mem­ branes, stimulate the adenylate cyclase-cyclic AMP system, thyroid hormone secretion, iodide organification, colloid droplet formation, glucose oxidation, and 32p incorporation into phospholipids. Prosta­ glandins of the E series are the most potent, although their maximal Format: Paperback.

    The authors have shown that the effect of cholera toxin in the production of cyclic 3', 5'-adenosine monophosphate (cAMP) in rabbit ileal mucosa reached its peak only after a lag period of 30 minutes duration; this delay was not shortened by the attempt to inhibit cyclic nucleotide phosphodiesterase with the exhibition of theophylline; it could also be shown that the effect of toxin in the Cited by:   Prostaglandins. ; 24(2). Laychock SG. Phospholipase A2 activity in pancreatic islets is calcium-dependent and stimulated by glucose.. Cell Calcium. ; 3(1). Garcia R, Laychock SG, Rubin RP. Inhibition of dibutyryl cyclic AMP induced steroidogenesis in rat adrenocortical cells by the putative calcium antagonist TMB

    Terms in this set () ________ are chemical messengers that are released by cells and transported in the bloodstream to alter the activities of specific cells in other tissues. Which of the following statements is true about paracrine communication? a. Many cells produce paracrine factors. b. It is used for the regulation of cell and organ.   Prostaglandin: One of a number of hormone-like substances that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of glandins are derived from a chemical called arachidonic acid.


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Prostaglandins and cyclic AMP by Symposium on the Medical Aspects of Prostaglandins and Cyclic AMP, University of Michigan 1972 Download PDF EPUB FB2

Most of the actions of prostaglandins in biological systems will be shown, at the molecular basis, to be mediated by changing levels of cyclic nucleotides. In this communication we have compared the effects of various cytoprotective prostaglandins on adenylate cyclase activity in biopsy specimens of corpus and antral mucosa in humans.

Basal enzyme activity in the whole homogenate (Billroth II resection material) averaged pmol of cyclic AMP formed per mg protein per 15 min. Figure 1. a shows the effects of ascending concentrations of prostaglandin E 2, prostaglandin F 2 ß, (S)-methyl- PG F 2 ß and prostaglandin D 2 on the gastric mucosal adenylate cyclase in homogenates of Billroth II resection : Bernd Simon, Horst Kather, Burkhard Kommerell.

COVID Resources. Reliable information about the coronavirus (COVID) is available from the Prostaglandins and cyclic AMP book Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus.

Abstract. Adenosine 3′,5′-monophosphate (cyclic AMP) is a ubiquitous nucleotide, having a myriad of biological effects. Tissue specificity of cyclic AMP actions is provided by the hormone-sensitive adenylate cyclase, located on the inner side of the plasma membrane which converts ATP to cyclic by: 1.

Biosynthesis of Prostaglandins. Prostaglandins and thromboxane A 2 (TXA 2), collectively termed prostanoids, are formed when arachidonic acid (AA), a carbon unsaturated fatty acid, is released from the plasma membrane by phospholipases (PLAs) and metabolized by the sequential actions of prostaglandin G/H synthase, or cyclooxygenase (COX), and respective by: Prostaglandins are known to regulate the female reproductive system, and are involved in the control of ovulation, the menstrual cycle and the induction of labour.

Indeed, manufactured forms of prostaglandins - most commonly prostaglandin E 2 - can be used to induce (kick-start) labour. Cyclic AMP provides information pertinent to cyclic adenosine 3',5'-monophosphate (AMP), a regulatory agent that controls the rate of a number of cellular processes.

This book discusses the heat-stable factor mediating the action of glucagon Book Edition: 1. Chapter IV Cyclic AMP and the Mechanism of Action of the Prostaglandins Chapter V Pharmacology and Therapeutic Applications of Prostaglandins in the Human Reproductive System Chapter VI Vasoactive and Anti-hypertensive Effects of Prostaglandins and other Renomedullary Lipids Chapter VII Prostaglandins and Respiratory Smooth MuscleBook Edition: 1.

Ramwell P.W., Rabinowitz I. () Interaction of Prostaglandins and Cyclic Amp. In: Rabin B.R., Freedman R.B. (eds) Effects of Drugs on Cellular Control Mechanisms.

Biological Council (The Co-ordinating Committee for Symposia on Drug Action).Cited by: The Hardcover of the Prostaglandins and Cyclic AMP: Biological Actions and Clinical Applications by Raymond H. Kahn at Barnes & Noble. FREE Shipping on B&N Outlet Membership Educators Gift Cards Stores & Events Help.

@article{osti_, title = {Regulation of cyclic AMP metabolism by prostaglandins in rabbit cortical collecting tubule cells}, author = {Sonnenburg, W.K.}, abstractNote = {In the rabbit cortical collecting tubule (RCCT), prostaglandin E/sub 1/ (PGE/sub 1/) and prostaglandin E/sub 2/ (PGE/sub 2/) at 1 nM inhibit arginine-vasopressin (AVP)-induced water reabsorption, while nM PGE/sub 1.

PDF | On Jan 1,C.-M. KUO and others published Circadian response of teleostean oocytes to gonadotropins and prostaglandin determined by cyclic AMP concentration | Find, read and cite all.

Get this from a library. The prostaglandins: pharmacological and therapeutic advances. [Maurice Frederick Cuthbert] -- The Prostaglandins: Pharmacological and Therapeutic Advances provides a concise account of the more important theoretical developments and areas in which the prostaglandins are being introduced into.

- Introduction.- - Cyclic AMP as the mediator of glucagon action in liver.- - Studies on the role of cyclic AMP in the hepatic actions of catecholamines using the isolated perfused rat liver.- - Studies on the role of cyclic AMP in catecholamine action using isolated liver parenchymal cells.- - A dual mechanism for catecholamine actions in liver.-Author: Jacques Dumont.

The reader is then introduced to unstable metabolites of arachidonic acid in relation to thrombosis; pharmacological interference in biotransformation of arachidonic acid; participation of prostaglandins in inflammatory pain; and factors affecting the formation and actions of cyclic AMP in blood platelets.

The prostaglandins (PG) are a group of physiologically active lipid compounds called eicosanoids having diverse hormone-like effects in glandins have been found in almost every tissue in humans and other animals. They are derived enzymatically from the fatty acid arachidonic acid.

Every prostaglandin contains 20 carbon atoms, including a 5-carbon ring. On the one hand, prosta glandins, a family of fatty acid derivatives first identified in human semen, have been shown to have great and varied effects on all aspects of human physiology due to activity at the cellular level as mediators in the formation of cyclic AMP.

The study of prostaglandins is considered today one of the most promising. of prostaglandins are secondary to their effects on cyclic nucleotides, there is little reason to think that this is true for all prostaglandin effects.

Recent work of Samuelsson and coworkers, in fact, indicates that in platelets, thromboxane A, causes agglutination without changes in. How to Cite. Conrad, K. and Dunn, M. Renal Prostaglandins and Other Eicosanoids.

Comprehensive Physiology. – @article{osti_, title = {Synthesis of prostaglandins by conjugate addition and alkylation of a directed enolate ion. 4,5-allenyl prostaglandins}, author = {Patterson, J W}, abstractNote = {Over the previous two decades many elegant syntheses of prostaglandins, which in more sophisticated forms, allow the stereospecific introduction of the various asymmetric carbons have been accomplished.

The level of cyclic AMP in primary cultures of bovine adrenal medulla cells is elevated by prostaglandin E1. Angiotensin II is commonly reported to act on receptors linked to phosphoinositide.increase the formation of an intracellular nucleotide known as cyclic adenosine monophosphate or cyclic AMP.

Increased levels of cyclic AMP are responsible for producing relaxation of bronchial smooth muscle (bronchodilation) Also, the formation and release of inflammatory mediators from mast cells are inhibited by increased levels of cyclic AMP.Prostaglandin D 2 receptor 2 (DP 2 or CRTH2) is a human protein encoded by the PTGDR2 gene and GPR DP 2 has also been designated as CD (cluster of differentiation ).

It is a member of the class of prostaglandin receptors which bind with and respond to various 2 along with Prostaglandin DP1 receptor are receptors for prostaglandin D2 (PGD2).Aliases: PTGDR2, CD, CRTH2, DL1R, DP2.